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Elevated hematocrit above 54% is a recognized indication to hold or reduce TRT dosing per Endocrine Society 2018 guidelines on testosterone therapy in men [1]

Pairing them with digestive enzymes or a little fiber can help, too

A number of musicians and actors told the Guardian that they personally knew high-profile people in their industries using Ozempic, although none would go on record

Obviously theres new drugs that are coming, new mechanisms, the GLP-1s, GIP, that really is going to continue to evolve and shift the game. The US Food and Drug Administration recently approved the Wegovy GLP-1 oral pill in December 2025