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Reduces systemic lipogenesis over extended 7-day half-life

This review provides a meticulous exploration of GLP-1, elucidating its origin, secretion, and the challenges associated with its clinical application due to its fragility in the presence of DPP-IV, resulting in a short half-life

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Clinical trials have demonstrated that patients using semaglutide for weight management can achieve an average weight reduction of approximately 15% of their initial body weight over 68 weeks, with some individuals achieving 20% or greater weight loss