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Personally, I find it can be extremely effective as a way to break plateaus during a cutting or bulking phase

This hormone works as an inflammatory agent, which means that is causes inflammation

doi: 10.1039/D0FO01954B 110

Low free testosterone and prostate Cancer risk: A collaborative analysis of 20 prospective studies

Nutrients 12(1): 236

Published in 2025, the study concluded that tesamorelin can lead to a significant reduction in such risk among people with HIV, a population whose likelihood of a cardiovascular event is twice as high compared to the general population.24 Skin health While you wont find any direct clinical studies on tesamorelin and skin health, there are several publications discussing the relationship between growth hormone, IGF-1, and skin-related health concerns