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Although the stimulation of GLP-1R has been shown to activate PI3K/AKT pathway in the PNS (Figure 1B)

While these mechanisms provide significant metabolic benefits for diabetes management and weight loss, they may also contribute to various side effects, including headaches

Dysbiosis is associated with systemic inflammation and metabolic dysfunction in diabetes, both of which can exacerbate DPN

The studies in humans on Se seminal levels show that, generally, infertile men tend to have lower levels of seminal plasma Se

Two studies also showed concomitant improvements in cognitive measures of recognition and working memory 122 and depressive-like behavior in rats administered antipsychotics 127

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