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10.1172/JCI95693 49 EckS.CastroM.SinibaldiD.WhiteW.FolliotK.GossageD.et al (2014)

Alpha-Lipoic Acid: This antioxidant may reduce oxidative stress in nerve cells

In vitro studies suggested that genistein treatment of human keratinocytes and fibroblasts modulates glutathione content and reactive oxygen species release, endothelial/inducible (e/i)NOS dependent nitric oxide release, MMP expression, and mitochondria membrane potential through mechanisms involving p38 MAPK, AKT and ERK1/2 as downstream signaling associated with membrane ERs and GPER, as well as by increasing SOD activity and BCL2 expression in endothelial cells (Savoia et al., 2018

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