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successfully introduced lactylation groups into two lysine residues of the p53 DNA-binding domain, systematically investigating their functional effects on p53 activity in vitro and in vivo

Clinica Chimica Acta 2012

For confocal microscopes, illumination intensity was limited to 0.1-0.2% of laser output to prevent phototoxicity, and the pinhole was set to allow optical slice at approximately 1-2 m

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Investigators use these peptides as tools to study endocrine feedback loops, pituitary signaling pathways, GH pulsatility, and downstream metabolic markers under controlled experimental conditions