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According to FDA prescribing information, these include: Nausea (occurring in 1544% of patients depending on formulation and dose) Vomiting (524% of patients) Diarrhea (830% of patients) Abdominal pain (511% of patients) Constipation (324% of patients) These gastrointestinal symptoms typically emerge during dose escalation and often diminish over time as physiological tolerance develops

10.1111/dom.16364 101 TianS.LeiY.ZhaoF.CheJ.WuY.LeiP.et al (2024)

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Pancreatitis: Some patients report inflammation of the pancreas, also known as pancreatitis, after taking semaglutide

Retatrutides glucagon receptor activation aids in weight loss by increasing the bodys use of stored energy, contributing to fat reduction

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