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In the recent decade, the finding that pro-inflammatory responses are controlled by neural circuits has given birth to the new concept of inflammatory reflex. The cholinergic anti-inflammatory pathway is the efferent or motor arm of the inflammatory reflex, the neural circuit that responds to and regulates the inflammatory response (15)

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Avoiding triggerssuch as certain social situations or environments where tobacco use is prevalentsignificantly reduces the likelihood of initiating or relapsing into tobacco use