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It is not clear whether sulfite is responsible for the accumulation of -AASA and the deficiency in PLP in ISOD and MocoD patients

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However, this association does not imply causationelevated B12 often serves as a biomarker for serious underlying disease rather than being directly harmful

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It's the most specific marker for liver injury

Isolation of primary chondrocytes from SD rats and intracellular ROS detection Primary chondrocytes isolated from SD rats using a collagenase digestion method as previously described and cultured in DMEM-F12 medium containing 10% FBS [3]