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239 Treatment with MAT2A inhibitors AG-24152 and AG-270 significantly reduces SAM levels, inhibits PRMT5 activity, and causes DNA damage and mitotic defects in tumor cells

Ann N Y Acad Sci 1478(1):317

In clinical practice, these vials are reconstituted with bacteriostatic water and drawn in precise microgram doses using insulin syringes

Apr 2012;35(8):876-893

Current evidence suggests that dysregulated T-cell responses and antigen recognition of neuronal proteins may contribute to disease processes, although the extent and significance of these effects require further investigation [80]

10.1128/MMBR.66.2.250-271.2002 Microbiol