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Common side effects: Injection site reactions (redness, itching, pain) most common, typically mild and transient Fluid retention or peripheral edema particularly in the first few weeks of treatment Joint pain (arthralgia) or myalgia Paresthesia (tingling sensations, often in extremities) Metabolic considerations: GH can cause mild increases in fasting glucose

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Detailed strain information is provided in Table S1

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J-NJ and X-XY performed most of the experiments