Retrieved 1 May 2024
[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Kim JY, Choi MJ, Ha S, Hwang J, Koyanagi A, Dragioti E, Radua J, Smith L, Jacob L, Salazar de Pablo G, Lee SW, Yon DK, Thompson T, Cortese S, Lollo G, Liang CS, Chu CS, Fusar-Poli P, Cheon KA, Shin JI, Solmi M
After feeding all branching pathways, the excess of glycolytic flux is converted to lactate to preserve a sufficient pool of NAD+ for glycolysis and also to avoid the tricarboxylic acid (TCA) cycle inhibition due to excess NADH
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Interestingly, combining vitamins A, C, D, and E with chemotherapy and radiotherapy offers a customized strategy for cancer treatment