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The big cigarette-ad campaigns of the nineteen-twenties were clearly aimed at a huge potential as well as an existing cigarette market, and slogans such as Reach for a Lucky Instead of a Sweet and Blow some my way were hardly devised merely to obtain a share of the existing market

Nicotine, the addictive substance in tobacco, alters brain chemistry, leading to dependency and withdrawal symptoms when attempting to quit

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The tendency to only increase when levels are below average may also be the case during aging, where efficient mitochondrial function is reduced

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