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For example, during excitotoxicity, the intracellular Ca 2+ concentration is abnormally elevated, leading to an excessive release of glutamate and a massive influx of Ca 2+ into the postsynaptic neuron, triggering an imbalance in Ca 2+ homeostasis and resulting in intracellular Ca 2+ overload

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According to the United States Food & Drug Administration (FDA), any polymer composed of 40 or fewer amino acids can be considered to be a peptide