Published analyses of the STEP trials (Wilding et al., NEJM 2021
Even tried fecal microbial transplant, which was preceded by a barrage of numerous oral antibiotics of virtually every class, followed by a night long laxative gut-prep as is done prior to a colonoscopy, then introducing the inoculant (donor feces) with a very long tube, to get it well up into the colon, once a day for a week
available in multiple bottle sizes
Scientific Reports, 12 (1), 1-9
Reserve concomitant prescribing of Hydrocodone Bitartrate and Acetaminophen Tablets and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate [see WARNINGS, PRECAUTIONS
Effect sizes on body weight, A1C, and cardiovascular endpoints vary by population, dose, and primary endpoint