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Contraindications (both): Active malignancy (GH may promote tumor growth) Acute critical illness Hypersensitivity to GHRH analogs Pregnancy and lactation Important : These are prescription peptides that require medical supervision

[DOI] [PubMed] [Google Scholar] 17.Traverso N., Ricciarelli R., Nitti M., Marengo B., Furfaro A.L., Pronzato M.A., Marinari U.M., Domenicotti C

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Proc Natl Acad Sci U S A 105:2085820863

Metformin has a boxed warning for lactic acidosis, a rare but potentially life-threatening buildup of lactic acid