In addition to physical exertion, fatigue can be brought on by conditions like arthritis, anemia, fibromyalgia, chronic fatigue syndrome, colds, flu, eating disorders, sleeping problems, autoimmune disorders, and diabetes
(The cost of B12 is pennies but the time for nurses to give the injection appears to be the saving here.) Some practices are enclosing diet sheets for patients to learn how to make sure they are eating foods containing B12
Vitamin B12 is commonly used by people that are deficient (known through blood work) or that are not able to get sufficient from their daily diet (some vegetarians)
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However, it can also be the result of low B6, low folate, renal failure, or hypothyroidism