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We demonstrated that TrkB signalling in these neurons is essential to maintain normal locomotor behaviour consistent with the initial hyperkinetic symptoms of HD and suggested that TrkB signalling deficiency may contribute effectively to HD motor symptoms 13

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[DOI] [PubMed] [Google Scholar] 49.Yoshinari M., Matsuzaka K., Hashimoto S., Ishihara K., Inoue T., Oda Y., Ide T., Tanaka T

Alpha-KGDH is also sensitive to oxidative stress and a number of metabolites modify the activity of KGDHC, including inactivation by 4-hydroxynonenal

Then, we review some case reports of less-studied substances

Besides that, this antioxidant stands out as an essential element, because it helps the body through detoxification, enzymes, tissue building, hormone production and even tissue repair