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Rejection of iQOS Reduced Risk Claim: Philip Morris is currently trying to gain FDA approval to start selling its heat-not-burn tobacco device called iQOS with a reduced risk claim in the US

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Exclusion criteria were any major recent psychiatric diagnosis, history of conditions that could affect the CNS at scanning other than HIV, daily anti-inflammatory use, unstable medical conditions, and pregnancy

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Stress avoidance of heavy lifting, isometric or strenuous upper body exercise

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