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Division of Endocrinology, Department of Medicine, Erasmus University Medical Center, Dr

The loss: CagriSema, Novo's next-generation combination of cagrilintide and semaglutide, failed its primary endpoint in the REDEFINE 4 head-to-head trial against tirzepatide

& Partridge, L

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In this meta-analysis, the author regretted the small number and the poor quality of the trials, with serious risk of bias associated with poor reporting of methods, imprecision and inconsistency