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In cells with NRF2 activation, most glutamate is secreted, and cystine is imported by the SLC7A11 (xCT) antiporter mechanism 47 (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, et al

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Those with MCI have greater risk of conversion to AD than the normal population, with conversion rates ranging from 10 to 36% over a 2-year period depending on the methods used and the population under study [5]