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Some trials reported enhanced physical performance (17) (20) , and improved aerobic capacity and exercise tolerance (32) whereas others yielded mixed results (37) (38) (39)

More broadly, it underscores a key principle in neuromodulationwhen brain stimulation changes both symptoms and circuits, it moves from hopeful therapy to mechanistic medicine

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That is the kind of insight memory cannot produce and a log makes obvious, and it changes the conversation from 'the medication stopped working' to 'here is the week-shape, what do we adjust?' 03Capy, for the Weeks the Noise Is Loud Some weeks the noise wins a few rounds - a dose change, a stressful stretch, the maintenance months when the effect can soften

For instance, Dersu Ozdemir and colleagues reported that natural withdrawal from opioids, such as morphine and fentanyl, can induce significant anxiety and depression-like behaviors [3,4]