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Utility of imaging-based biomarkers for glutamate-targeted drug development in psychotic disorders: a randomized clinical trial

Development of GLP-1GIPLani We previously showed that covalent attachment of the PPAR/ co-agonist Tesa to a pharmacokinetically optimized GLP-1R agonist enabled targeted delivery of Tesa into GLP-1R-expressing cells, leading to greater weight loss and further improvement of glucose control relative to treatment with pharmacokinetically-matched GLP-1R agonist backbone 26 (Extended Data Fig

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The list of differentially expressed proteins was then subjected to GO functional enrichment and KEGG pathway enrichment analyses

These symptoms may indicate the need to increase consumption of vitamin A foods or improve absorption through better digestive health

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