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SURMOUNT-1 (tirzepatide) data SURMOUNT-1 (N=2,539) tested tirzepatide 5, 10, and 15 mg against placebo over 72 weeks, reporting 15.0%, 19.5%, and 20.9% mean weight loss at the three doses respectively [2]

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Shin et al., 2003), mice with homozygous or heterozygous knockout of Drd3 showed elevated blood pressure as a result of elevated renal renin production and sodium retention (Asico et al., 1998

10.1038/nature13148 94 MancusoR

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