At the cellular level, B12 acts as a cofactor for two critical enzymatic reactions: Methionine synthase converts homocysteine to methionine, essential for DNA methylation and synthesis Methylmalonyl-CoA mutase involved in fatty acid metabolism and myelin production By restoring adequate B12 levels, injections enable normal red blood cell maturation in the bone marrow, correcting the megaloblastic anaemia
Spearmans correlation was performed for analysis between the quantitative covariates and the outcome
For a 100 kg (220 lb) patient, this translates to a daily target of at least 80 g per day , which is usually manageable if patients aim for 20 to 30 grams at each meal
It's good to check your blood sugar often
(typically seen when niacin therapy is started, can be avoided by coadministration of aspirin) [17] Hyperuricemia, podagra Hyperglycemia Possibly: nausea, vomiting, pruritus, hives [12] Therapeutic use Dyslipidemia: Niacin lowers VLDL and increases HDL serum levels (see Second-line lipid-lowering agents)
Alcohol and Alcoholism
