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These two effects are what make the drug so useful for weight loss but they are also the reason why some people experience digestive discomfort, especially in the early weeks

B12 Pairing Standard GLP-1 depletes B12 as food intake drops

Many people have turned to the diabetes drug Ozempic in the hope it will help them lose weight

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doi: 10.1016/0026-0495(94)90209-7 28 TeedeHJTayCTLavenJDokrasAMoranLJPiltonenTTet al

North America dominated the market share in 2025