Rezamahaleh FA, Khadivzadeh T, Asgharinekah SM, Esmaeili H
doi: 10.1016/j.freeradbiomed.2018.09.043 9 CobinePABradyDC
Its serendipitous discovery as a weight-loss aid mirrors bariatric surgery, which is founded on the finding that patients undergoing stomach (gastric) surgery in the 50s for ulcer disease all lost weight
The medication itself substantially reduces appetite, which makes eating less feel natural rather than effortful for most patients
The storage duration can vary depending on the specific product and manufacturer guidelines
Using click chemistry, we incorporated a biotin tag that facilitated streptavidin pulldown of proteins covalently modified by our probes, followed by quantitative mass spectrometry (MS) for target identification