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This rapid clearance may help prevent the toxic accumulation of mediators in the bloodstream, significantly reducing the severity and duration of systemic MCAS flares, such as flushing, gastrointestinal distress, and neurological inflammation

General Guidelines Keep vials away from excessive heat and prolonged light exposure

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The antibodies used in this study are listed in Table 1

J Infect 57(1):9092 Baltazard T, Dhaille F, Duvert-Lehembre S, Lok C, Chaby G (2017) Trimethoprim-sulfamethoxazole-induced linear IgA bullous disease presenting as toxic epidermal necrolysis