Yes, exercise can trigger mast cell degranulation in some individuals, a phenomenon sometimes called exercise-induced histamine release
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Concerning NO production, inhibitory methylarginines are formed by protein arginine methyltransferases (type I PRMT and type II PRMT) via immediate precursor protein MMA, then it is catabolized to ADMA (type I PRMT) and SDMA (type II PRMT)
6K-T1, 6N)
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Pollard et al