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10.1021/jf3025634 147 ShimonoM.SuganoS.NakayamaA.JiangC

Other clinical bispecific mAbs, retaining the Fc for half-life extension, require additional mutations, including in the CH3 domain of the Fc to generate heterodimers (e.g., Fab-arm exchange/knobs-into-holes), as well as LALA or STR mutations to limit endogenous FcR interaction

Gastroparesis is a condition in which the stomach empties its contents into the small intestine more slowly than normal

This refill is designed for those who already own the original

Puccetti, R

Your clinician reviews your health profile to decide if it's a fit, then walks you through application