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Unlike oral supplements that may take weeks to absorb and are often less effective due to digestive limitations injectable B12 works quickly and efficiently

ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis

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It also indirectly reduces oxidative stress by regenerating vitamins C and E and acting as a cofactor for other antioxidants in the body

Shirsath N, Rathos M, Chaudhari U, Sivaramakrishnan H, Joshi K