For instance, copper is required for the activation of MEK1 kinase, and disruption of this copper-dependent signaling contributes directly to myofibrillar disorganization and pathological hypertrophy [182, 183]
Copper deficiency impairs mitochondrial respiration, antioxidant defense, and vascular structural integrity, whereas copper overload triggers oxidative stress, inflammatory responses, and aberrant activation of cell death signaling
Note: The information provided here is meant for general educational purposes only and is not intended to be medical advice
We are monitoring global reports to keep patients informed
Nat Commun (2020) 11(1):698
Both patients and the doctors helping them should be aware of important details