Studies have indicated targeting ferroptosis with specific drugs promotes adaptive cell repair and ameliorates fibrosis, suggesting drug intervention in ferroptosis as a potential avenue for preventing kidney fibrosis [21]
Currently approved options include orlistat, naltrexone/bupropion (Mysimba note that NHS commissioning of this medicine varies by local area), and semaglutide (Wegovy), which has a NICE technology appraisal recommendation for weight management
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GHK (also known as tripeptide-1), comprising three amino acids, namely - glycine, histidine and lysine