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The reduction of H 2 O 2 by the selenides mechanism may involve a redox shuttle between the selenides and spirodiazaselenuranes via the corresponding intermatidates selenoxides (Figure 5)

Differences between the investigated tissue types may relate to the fact that the cardiac model contains iPSC-derived human cardiomyocytes that are still maturing, while the hepatic model contains mature human hepatocytes

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