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Once inside the hepatocyte, bilirubin binds to intracellular proteins, including glutathione S-transferases, which stabilize the molecule and prevent it from diffusing back into circulation [25]

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From Pubchem Synonyms: PEG IGF-1 Ec, PEG myotrophin, Pegylated MGF, Molecular Formula: C121H200N42O39 Sequence: PEG-Suc-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-Cys CAS number: 307297-39-8 PubChem CID: 178101669 MGF, as a variant of IGF-1, binds to the IGF-1 receptor (IGF-1R) that initiates a series of intracellular signaling events

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Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-CTF (C99)