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Some companies are looking beyond GLP-1 and other hot targets like GIP and glucagon to emerging areas like amylin, another hormone produced in the pancreas that helps people feel full

Drug repurposing and novel therapeutic strategies The crosstalk between proteostasis machineries offers numerous opportunities for drug repurposing

Rapid weight loss from GLP-1 medications can be accompanied by a loss of lean body mass

3.5-3.6 min, 10-99% A

To further explore the role of neurotransmitters in modulating interstitial fluid clearance, CSF tracers were injected directly into brain parenchyma 150-200 m below the skull surface and two-photon imaging of tracer clearance performed over 60 minutes with intervals of 15 minutes (Fig