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doi: 10.4269/ajtmh.20-0473 223 ProalA

HIV-associated wasting prevalence in the era of modern antiretroviral therapy

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In chicken liver, copper exposure inactivates the Nrf2/Kelch-like ECH-associated protein 1 (KEAP1) signaling pathway, reduces the expression of its downstream gene targets such as xCT and GPX4, disrupts the endogenous antioxidant GSH metabolism, promotes lipid peroxidation and induces the typical morphological characteristics in mitochondria associated with ferroptosis

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Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction