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The authors reported that this blunted dopamine response was caused by increased inhibitory synaptic transmission onto dopamine neurons 21

This potential underestimation may therefore threaten the validity of the overall harm-ranks of these specific substances

After backfilling losses in existing tobacco excise tax revenue (described in more detail below), the new cigarette excise tax would generate an estimated $500 million to $750 million in net revenue in 201516 for the purposes described in the measure

Other chemicals, such as ammonia and pesticides, are used in a smaller quantity

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