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Weight loss can vary depending on a patients response to the medication and ability to make lifestyle changes

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[13] These findings are further reinforced by pharmacovigilance data from the FDA Adverse Event Reporting System (FAERS) database (n=48,214 reports), where GLP-1RA-related gastrointestinal adverse events, including nausea (9651 vs 38,030) and vomiting (4383 vs 17,062), were lower with combination therapy compared to GLP-1RA monotherapy, suggesting improved tolerability when metformin is added

Ethical consideration Ethical approval was obtained from the Institutional Review Committee, General Hospital, Ilorin, Kwara State, before the commencement of this study (Reference number: GHI/IRC/246/VOL.I.02)

Beneficial Microbes, 8 (4), 569-578

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