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Although codon 642 is located out of the JMD, amino acid aberrations in this position are thought to destabilize the JMD through amino acid interactions (81)

Importantly, many patients find these taste changes helpful rather than problematic, as they facilitate adherence to reduced-calorie diets and support weight management goals

Vitamin C, known for its brightening properties, further amplifies these effects by promoting collagen production, improving skin texture, and providing a protective barrier against environmental stressors