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Although several theories with empirical support tackle the point, the causes of BIPN are multifactorial and not fully understood, it remains a potentially persistent adverse event that can lead to long-term objective neurological dysfunction (Li et al., 2020), thereby reducing the quality of life, weakening physical function, causing delays or dose reductions in chemotherapy, and in some cases even interrupting treatment, imposing a huge economic burden (Selvy et al., 2021)
In particular, oxidative modifications to proteins have actually been proposed as a potential factor in the onset and progression of several psychiatric disorders, including anxiety and depressive disorders
"Lilly's advertising campaign deprives consumers of the truthful, current, and complete information they need to make informed decisions about their available treatment options," the suit said
They can also come in nonstandard doses or alternative dosage forms, such as sublingual (under the tongue) tablets or drops
A few therapies are approved to treat ALS, but their ability to slow disease progression and extend survival is limited
