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Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells

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The signaling pathways involved in this immune modulation include the Toll-like receptor (TLR) signaling pathway, which recognizes microbial-associated molecular patterns (MAMPs) and activates downstream signaling cascades that regulate immune responses (110)

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Goiter: the pathophysiology of many conditions and the mechanisms of gland dysfunction, such as the abnormal enlargement of the thyroid gland called goiter, can be induced experimentally in animal models