Several hypotheses are being explored: Neuroplasticity effects: Chronic activation of amylin pathways may strengthen neuronal networks that favor satiety over hunger
Ceriello A et al
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These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations
Common Side Effects of BPC 157 While generally well-tolerated, some individuals may experience mild side effects, including: Nausea Vomiting Diarrhea Abdominal discomfort Rare side effects, such as rash or fatigue, could indicate an allergic reaction and should be addressed promptly
sadly, many patients develop severe fatal outcomes because of overwhelming inflammation known as cytokine storm (248, 249), that leads to ROS-mediated cell death and tissue damage typical of RNA viruses (250)
