Scientists Joel Habener , Svetlana Mojsov , and Lotte Bjerre Knudsen were awarded the 2024 Lasker Award for their discovery and development of GLP-1-based treatments that have revolutionized the obesity and diabetes new medications
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36 The causes of the initial acute pancreatitis episodes, before starting GLP-1 receptor agonist therapy, were idiopathic in 77 patients (48%), gallstones in 49 (30%), alcohol use in 21 (13%), hypertriglyceridemia in 9 (6%), and medication related in five (3%)
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Its stability-enhancing N-terminal modification allows for effective subcutaneous administration, and it is FDA-approved for HIV-related lipodystrophy