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How GLP-1 Medications Affect Your Body During Exercise GLP-1 receptor agonists like semaglutide work through several mechanisms that directly influence how your body responds to physical activity

This improvement in body composition is an important therapeutic goal because increased lean soft tissue mass is associated with increased insulin sensitivity 30 , improved metabolic health and increased life expectancy 31

In the context of DR, this leads to the phosphorylation of ERK1/2, increasing downstream expression of anti-apoptotic genes like BCL2 and reducing the activity of pro-apoptotic markers such as Caspase-3

According to FDA prescribing information, injection site reactions occur in approximately 1.4% of patients using Ozempic and 2.4% of patients using Wegovy

Follow your clinicians guidance Your doctor can provide personalised advice based on your health, side effects and other medications

However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional