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Benowitz NL, Nardone N, Dains KM, Hall SM, Stewart S, Dempsey D et al (2015)

Since menthol makes smoke feel less harsh and easier to inhale, it is one of the most pervasive and insidious flavors available

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Tobacco ( Nicotiana tabacum ) is a plant often considered for use as a bio-factory in generating medicines and vaccines, while the CRISPR-Cas nuclease technology allows the induction of site-specific double-strand breaks for better homologous recombination-mediated gene targeting