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In conclusion: in the light of the irreversibility of the symptoms and the possible invalidity as a result of undertreatment it is important to supply adequate supplementation (intramuscular) when there is evident symptomology

And the specific adjustments that separate mediocre results from optimal outcomes

Therefore, before supplementation is stopped, it is possible, and even recommended, to exceed normal serum cobalamin concentrations in treated patients [46]

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