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3 In addition to the high mortality rate, HE imposes a great burden on various aspects of patient lives and healthcare systems

November 2025, Janet Iwasa

Tremendous investment is being made by pharmaceutical and biotech firms into these medications in a race for the next so-called lifestyle drug, as both patients and practitioners are given new hope in the ability to reverse decades of physical, psychological and lifestyle influence of established behavior patterns

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Despite decades of lifestyle-based interventions, long-term weight loss has proven elusive for many, driving an urgent need for safe and effective medical therapies