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Eli Lilly's direct-to-patient program for brand-name Zepbound vials at lower cash-pay pricing than retail pharmacies

Yosipovitch G, Loh KC, Hock OB

Choline transporters, such as the high-affinity choline transporter (CHT1), facilitate choline uptake into cells

GIP receptors are found throughout the body, and their activation improves how cells respond to insulin (insulin sensitivity) and appears to promote more favorable fat distribution (less visceral fat around organs, more subcutaneous fat under the skin)

Targeting the DNA repair endonuclease ERCC1-XPF with green tea polyphenol epigallocatechin-3-gallate (EGCG) and its prodrug to enhance cisplatin efficacy in human cancer cells

Our study revealed that SKN-1 is induced by the accumulated fat in all three sterile mutants, irrespective of the lifespan phenotype, consistent with the known role of SKN-1 in responding to lipid toxicity 16