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The ACO1 gene is located on chromosome 9p21.1 and is composed of 23 exons that generate three alternatively spliced mRNAs, each of which encode the same protein of 889 amino acids

Tissue-intrinsic circadian clocks govern a wide range of molecular processes involved in the adjustment of tissue physiology over the course of the circadian cycle (reviewed in (47))

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Plastoglobuli are in close contact with thylakoid membranes and serve as biosynthesis and storage subcompartments, for example for carotenoids and xanthophylls (Austin et al

Its deficiency can be encountered by vegetarians, the elderly, patients with diabetes mellitus, and people with pernicious anemia